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Chembl MCP Server

by Cyanheads
Developer ToolsLow Risk9.9MCP RegistryLocalRemote
Free

Server data from the Official MCP Registry

Link compounds to protein targets, rank bioactivity, and look up drug mechanisms and indications.

About

Link compounds to protein targets, rank bioactivity, and look up drug mechanisms and indications.

Remote endpoints: streamable-http: https://chembl.caseyjhand.com/mcp

Security Report

9.9
Low Risk9.9Low Risk

Valid MCP server (1 strong, 1 medium validity signals). No known CVEs in dependencies. Package registry verified. Imported from the Official MCP Registry. Trust signals: 8 highly-trusted packages.

7 tools verified · Open access · 2 issues found

Security scores are indicators to help you make informed decisions, not guarantees. Always review permissions before connecting any MCP server.

Permissions Required

This plugin requests these system permissions. Most are normal for its category.

HTTP Network Access

Connects to external APIs or services over the internet.

What You'll Need

Set these up before or after installing:

Set to 'duckdb' to enable the bioactivity DataCanvas spill and the chembl_dataframe_* SQL tools. When 'none', large bioactivity sets inline a preview but never spill.Optional

Environment variable: CANVAS_PROVIDER_TYPE

Base URL for the ChEMBL REST data API. Override for a private mirror or pinned host.Optional

Environment variable: CHEMBL_API_BASE_URL

Per-request timeout in milliseconds for upstream ChEMBL fetches.Optional

Environment variable: CHEMBL_REQUEST_TIMEOUT_MS

ChEMBL per-page cap when streaming activity pages for the bioactivity spill (max 1000).Optional

Environment variable: CHEMBL_MAX_PAGE_SIZE

Default result limit applied when callers omit it.Optional

Environment variable: CHEMBL_DEFAULT_LIMIT

Ceiling on rows chembl_get_bioactivities stages to a DataCanvas table, and so on the upstream page drain behind it. Over the cap the response reports truncated: true.Optional

Environment variable: CHEMBL_MAX_SPILL_ROWS

Set to 'true' to register the opt-in chembl_dataframe_drop tool (absent from tools/list when off).Optional

Environment variable: CHEMBL_DATAFRAME_DROP_ENABLED

Sets the minimum log level for output (e.g., 'debug', 'info', 'warn').Optional

Environment variable: MCP_LOG_LEVEL

The hostname for the HTTP server.Optional

Environment variable: MCP_HTTP_HOST

The port to run the HTTP server on.Optional

Environment variable: MCP_HTTP_PORT

The endpoint path for the MCP server.Optional

Environment variable: MCP_HTTP_ENDPOINT_PATH

Authentication mode to use: 'none', 'jwt', or 'oauth'.Optional

Environment variable: MCP_AUTH_MODE

How to Install & Connect

Available as Local & Remote

This plugin can run on your machine or connect to a hosted endpoint. during install.

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