How do I install Ensembl?

Ensembl supports both local and remote installation. For local use, install it via npm (npx) and add the configuration to your AI app. For remote access, add the server URL to your MCP configuration.

What credentials does Ensembl need?

Ensembl requires the following credentials or environment variables: ENSEMBL_BASE_URL, MCP_LOG_LEVEL, MCP_HTTP_HOST, MCP_HTTP_PORT, MCP_HTTP_ENDPOINT_PATH, MCP_AUTH_MODE. You can find setup instructions on the server detail page.

What AI apps work with Ensembl?

Ensembl uses the Model Context Protocol (MCP) and works with any MCP-compatible AI app, including Claude, ChatGPT / Codex, Gemini, Copilot, Cursor, and more.

Back to Browse

Ensembl MCP Server

by Cyanheads

Developer ToolsLow Risk10.0MCP RegistryLocalRemote

Free

Server data from the Official MCP Registry

Look up genes, fetch sequences, predict variant consequences, find orthologs and xrefs via Ensembl.

About

Look up genes, fetch sequences, predict variant consequences, find orthologs and xrefs via Ensembl.

Remote endpoints: streamable-http: https://ensembl.caseyjhand.com/mcp

Security Report

10.0

Low Risk10.0Low Risk

Valid MCP server (1 strong, 1 medium validity signals). No known CVEs in dependencies. Package registry verified. Imported from the Official MCP Registry. Trust signals: 6 highly-trusted packages.

7 tools verified · Open access · 1 issue found

Security scores are indicators to help you make informed decisions, not guarantees. Always review permissions before connecting any MCP server.

Permissions Required

This plugin requests these system permissions. Most are normal for its category.

HTTP Network Access

Connects to external APIs or services over the internet.

What You'll Need

Set these up before or after installing:

Ensembl REST API base URL. Override to use GRCh37 endpoint or a local mirror.Optional

Environment variable: ENSEMBL_BASE_URL

Sets the minimum log level for output (e.g., 'debug', 'info', 'warn').Optional

Environment variable: MCP_LOG_LEVEL

The hostname for the HTTP server.Optional

Environment variable: MCP_HTTP_HOST

The port to run the HTTP server on.Optional

Environment variable: MCP_HTTP_PORT

The endpoint path for the MCP server.Optional

Environment variable: MCP_HTTP_ENDPOINT_PATH

Authentication mode to use: 'none', 'jwt', or 'oauth'.Optional

Environment variable: MCP_AUTH_MODE

How to Install & Connect

Available as Local & Remote

This plugin can run on your machine or connect to a hosted endpoint. during install.

Reviews

No reviews yet

Be the first to review this server!

More Developer Tools MCP Servers

Fetch

Free

by Modelcontextprotocol · Developer Tools

Web content fetching and conversion for efficient LLM usage

Git

Free

by Modelcontextprotocol · Developer Tools

Read, search, and manipulate Git repositories programmatically

Toleno

Free

by Toleno · Developer Tools

Toleno Network MCP Server — Manage your Toleno mining account with Claude AI using natural language.

Ensembl MCP Server

About

Security Report

Findings (1)

Permissions Required

What You'll Need

How to Install & Connect

Reviews

No reviews yet

More Developer Tools MCP Servers

Fetch

Git

Toleno

mcp-creator-python

MarkItDown

FinAgent