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Complex Portal MCP Server

Developer ToolsModerate5.2MCP RegistryLocalRemote
Free

Server data from the Official MCP Registry

EBI Complex Portal MCP.

About

EBI Complex Portal MCP.

Remote endpoints: streamable-http: https://gateway.pipeworx.io/complex-portal/mcp

Security Report

5.2
Moderate5.2Moderate Risk

The mcp-complex-portal server is a keyless wrapper around the EBI Complex Portal web service with two read-only tools (search_complexes, get_complex), and its network access matches its purpose. The visible source shows no exfiltration, shell execution, or hardcoded secrets, though the source was truncated before the tool implementations and the package's bin/cli.js were reviewed. The README's note that tools/list also exposes shared gateway meta-tools is a disclosure point to be aware of rather than a vulnerability. Supply chain analysis found 5 known vulnerabilities in dependencies (0 critical, 3 high severity).

3 files analyzed · 9 issues found

Security scores are indicators to help you make informed decisions, not guarantees. Always review permissions before connecting any MCP server.

Permissions Required

This plugin requests these system permissions. Most are normal for its category.

HTTP Network Access

Connects to external APIs or services over the internet.

How to Install & Connect

Available as Local & Remote

This plugin can run on your machine or connect to a hosted endpoint. during install.

Documentation

View on GitHub

From the project's GitHub README.

mcp-complex-portal

EBI Complex Portal MCP.

Part of Pipeworx — an MCP gateway connecting AI agents to 1854+ live data sources. This is an independent, unofficial integration — not affiliated with, endorsed by, or published by the upstream provider.

Tools

ToolDescription
search_complexesSearch the EBI Complex Portal — a manually curated database of stable macromolecular protein complexes — by protein/complex name, gene, GO term, or biological process (e.g. "apoptosis", "SCF", "ribosome"). Returns matching complexes with their accession (e.g. CPX-7762), name, description, and organism. Keyless. Complements UniProt/IntAct/STRING.
get_complexGet a single Complex Portal record by its accession (e.g. CPX-7762). Returns the complex's participants (subunits) with UniProt identifiers, biological roles and stoichiometry, plus systematic name, function, species, and description. Keyless. Complements UniProt/IntAct/STRING.

Quick Start

Add to your MCP client (Claude Desktop, Cursor, Windsurf, etc.):

{
  "mcpServers": {
    "complex-portal": {
      "url": "https://gateway.pipeworx.io/complex-portal/mcp"
    }
  }
}

What this endpoint actually serves

tools/list at https://gateway.pipeworx.io/complex-portal/mcp returns the tools in the table above plus the shared Pipeworx meta-tools — ask_pipeworx, discover_tools, search_within, remember/recall and the rest of the gateway-wide set. So the tool count you see is larger than this table: a single-pack endpoint currently lists roughly 30 shared tools alongside the pack's own. The connection's initialize response states its exact scope, and is the authoritative answer for a given day.

This is deliberate, not multiplexing by accident. The meta-tools are what let a scoped connection answer a question this pack does not cover — via ask_pipeworx, which routes across the whole catalog — without you adding a second MCP server. There is currently no way to mount a pack endpoint without them; if the extra schemas cost you more context than the routing is worth, connect to the full gateway once rather than to several pack endpoints.

Or connect to the full Pipeworx gateway to get every pack's tools listed directly, instead of just this one's:

{
  "mcpServers": {
    "pipeworx": {
      "url": "https://gateway.pipeworx.io/mcp"
    }
  }
}

Both URLs reach the same gateway and the same 1854+ data sources. The only difference is which pack's tools are listed directly; ask_pipeworx reaches all of them from either one.

No MCP client? Call it over HTTP

curl -X POST https://gateway.pipeworx.io/v1/tools/search_complexes \
  -H 'Content-Type: application/json' \
  -d '{"query":"ribosome"}'

No account needed for the first calls. Inspect any tool: GET https://gateway.pipeworx.io/v1/tools/search_complexes. Find one: POST https://gateway.pipeworx.io/v1/tools/search_packs with {"query":"..."}.

Standalone (no gateway account)

This package also runs as a local stdio MCP server — no Pipeworx account, no gateway round-trip:

{
  "mcpServers": {
    "complex-portal": {
      "command": "npx",
      "args": ["-y", "@pipeworx/mcp-complex-portal"]
    }
  }
}

Or run it directly to confirm it starts:

npx -y @pipeworx/mcp-complex-portal

It speaks MCP over stdin/stdout and answers initialize/tools/list/tools/call for only this pack's tools — none of the shared meta-tools the gateway connection above adds. Same source, same tools, no ask_pipeworx routing.

Using with ask_pipeworx

Instead of calling tools directly, you can ask questions in plain English — this works on the pack endpoint above as well as on the full gateway:

ask_pipeworx({ question: "your question about Complex Portal data" })

The gateway picks the right tool and fills the arguments automatically.

More

License

MIT

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