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Monarch Initiative MCP Server

Developer ToolsLow Risk10.0MCP RegistryRemote
Free

Server data from the Official MCP Registry

Monarch biomedical knowledge graph — diseases, phenotypes, genes, variants

About

Monarch biomedical knowledge graph — diseases, phenotypes, genes, variants

Remote endpoints: streamable-http: https://gateway.pipeworx.io/monarch-initiative/mcp

Security Report

10.0
Low Risk10.0Low Risk

Valid MCP server (1 strong, 0 medium validity signals). No known CVEs in dependencies. Imported from the Official MCP Registry. Trust signals: trusted author (392/393 approved). 1 finding(s) downgraded by scanner intelligence.

16 tools verified · Open access · 1 issue found

Security scores are indicators to help you make informed decisions, not guarantees. Always review permissions before connecting any MCP server.

Permissions Required

This plugin requests these system permissions. Most are normal for its category.

HTTP Network Access

Connects to external APIs or services over the internet.

How to Connect

Remote Plugin

No local installation needed. Your AI client connects to the remote endpoint directly.

Add this to your MCP configuration to connect:

{
  "mcpServers": {
    "io-github-pipeworx-io-monarch-initiative": {
      "url": "https://gateway.pipeworx.io/monarch-initiative/mcp"
    }
  }
}

Documentation

View on GitHub

From the project's GitHub README.

@pipeworx/monarch-initiative

Monarch Initiative MCP — biomedical knowledge graph linking diseases, phenotypes, genes, and variants across species. Keyless.

Part of Pipeworx — an MCP gateway connecting AI agents to 1394+ live data sources.

Tools

  • search(query, category?, limit?, offset?) — full-text node search
  • entity(id) — single node by curie (e.g. MONDO:0007947)
  • associations(entity_id, category?, predicate?, direction?, limit?) — associations involving an entity
  • phenotype_to_gene(phenotype_id) — gene candidates for a phenotype (HP:…)
  • gene_to_disease(gene_id) — diseases associated with a gene

Data source

https://api.monarchinitiative.org/v3/api/

Quick Start

Add to your MCP client (Claude Desktop, Cursor, Windsurf, etc.):

{
  "mcpServers": {
    "monarch-initiative": {
      "url": "https://gateway.pipeworx.io/monarch-initiative/mcp"
    }
  }
}

Or connect to the full Pipeworx gateway for access to all 1394+ data sources:

{
  "mcpServers": {
    "pipeworx": {
      "url": "https://gateway.pipeworx.io/mcp"
    }
  }
}

Using with ask_pipeworx

Instead of calling tools directly, you can ask questions in plain English:

ask_pipeworx({ question: "your question about Monarch Initiative data" })

The gateway picks the right tool and fills the arguments automatically.

More

License

MIT

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Monarch Initiative MCP Server - Monarch biomedical knowledge graph — diseases, phenotypes, | MCP Marketplace