About
UniProt MCP — protein sequence + function database.
Remote endpoints: streamable-http: https://gateway.pipeworx.io/uniprot/mcp
Security Report
Valid MCP server (1 strong, 0 medium validity signals). No known CVEs in dependencies. Imported from the Official MCP Registry. Trust signals: trusted author (1062/1065 approved). 1 finding(s) downgraded by scanner intelligence.
36 tools verified · Open access · 1 issue found
Security scores are indicators to help you make informed decisions, not guarantees. Always review permissions before connecting any MCP server.
Permissions Required
This plugin requests these system permissions. Most are normal for its category.
How to Connect
Remote Plugin
No local installation needed. Your AI client connects to the remote endpoint directly.
Add this to your MCP configuration to connect:
{
"mcpServers": {
"io-github-pipeworx-io-uniprot": {
"url": "https://gateway.pipeworx.io/uniprot/mcp"
}
}
}Documentation
View on GitHubFrom the project's GitHub README.
@pipeworx/uniprot
UniProt MCP — the canonical protein-sequence and -function knowledge-base from EBI. Keyless.
Part of Pipeworx — an MCP gateway connecting AI agents to 1394+ live data sources.
Tools
search(query, format?, size?)— UniProtKB search (Lucene-style query)get(accession, format?)— single entry by accession (e.g. P12345)proteomes_search(query, size?)— search proteomestaxonomy_search(query, size?)— search NCBI taxonomy as exposed by UniProtkeyword(keyword_id)— UniProt keyword infofeature_summary(accession)— summary of feature annotations (domain, mutagen, etc)
Data source
https://rest.uniprot.org/ — public, no API key.
Quick Start
Add to your MCP client (Claude Desktop, Cursor, Windsurf, etc.):
{
"mcpServers": {
"uniprot": {
"url": "https://gateway.pipeworx.io/uniprot/mcp"
}
}
}
Or connect to the full Pipeworx gateway for access to all 1394+ data sources:
{
"mcpServers": {
"pipeworx": {
"url": "https://gateway.pipeworx.io/mcp"
}
}
}
Using with ask_pipeworx
Instead of calling tools directly, you can ask questions in plain English:
ask_pipeworx({ question: "your question about Uniprot data" })
The gateway picks the right tool and fills the arguments automatically.
More
License
MIT
Reviews
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